Rise in Companion Diagnostics Market is Expected to Reach USD 130 Billion in 2018: Transparency Market Research

The global companion diagnostics market will be valued at $ 5.6 billion in 2019. It is expected to grow at a CAGR of 18.1% from 2013 to 2019, and was valued at $ 1.8 billion in 2013, according to a research report published by Transparency Market Research.

The research report, titled “Companion Diagnostics Market (Breast Cancer, Lung Cancer, Colorectal Cancer, Gastric Cancer, Melanoma and Others) – Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 – 2019”, fully explores current and future possibilities in the growing segment of companion diagnostics.

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The report states that the companion diagnostics market for breast cancer was the dominant sector in 2012, in terms of revenue. The upcoming sector for the near future is lung cancer. The segment is growing at a CAGR of more than 20% between 2013 and 2019. The report cites reasons for growth as the discovery of lung cancer specific biomarkers, along with a myriad of relevant companion diagnostics.

The largest market according to region in 2012 was North America, with the E.U. in following. The report said that the factors that favored the market’s growth were positive healthcare policies, a growing consumer base, increasing disposable incomes, improvements in healthcare systems, and increased awareness. The acceptance of modern medicine into mainstream sectors in the U.S. and the E.U. are the prime reasons for the growth of this market. The Asia-Pacific region and the Rest of the World regions are set to show considerable growth by the year 2019. The report cites untapped potential, increasing disposable incomes, and an improving healthcare infrastructure.

The report explains that companion diagnostics are tests which assist physicians while making decisions regarding the most efficient treatment methods, depending on responses by the patient over ongoing treatment.

Key restraints as explained by the report include regulatory restrictions, commercialization of companion diagnostics, heavy procedure costs, long phases of approval, and lack of reach towards the low income countries.

Key companies in the companion diagnostics market include Quagen N.V., Abbott Laboratories, Life Technologies, Genomic Health, Inc., GE Healthcare Ltd., Roche Holdings AG, Agilent Technologies, Inc., and Agendia N.V.

The report provides exhaustive details on the companion diagnostics market by segmenting it according to indications and geography. By indications, the market is classified into breast cancer, lung cancer, melanoma, gastric cancer, colorectal cancer, and others such as HIV and thalassemia. According to geography, the reports details North America, Europe, Asia-Pacific, and Rest of the World.

Colon Hydrotherapy: Frequently Asked Questions

Did you know that colon cancer is the second leading cause of cancer related deaths in the United States? It may seem surprising and a bit devastating, but is very true. eMedTV, a medical informational resource, confirms this fact in one of its findings. Looking at the gravity of this disease, the American Cancer Society had predicted that approximately 148,610 people would be diagnosed with colon cancer and 55,170 of them would die of it in 2006. Whether this prediction proved true is a different issue, but what is more important here is to find a way to prevent this problem. Colon hydrotherapy is a clinical procedure that is recommended by most health experts to improve colon health. Patients who have undergone this therapy have reported a noticeable recovery from their colon related ailments.

Colon Hydrotherapy: Which Conditions Lead to Colon Cancer?
Conditions that may not look very grim initially may ultimately lead to a deadly disease called colon cancer. These conditions include:Recurring constipationBlood in stoolDiverticulitisIrritable bowel syndromeDiarrheaColon hydrotherapy is an effective way to treat all these health problems. If due attention is paid at the earlier stage, colon cancer can be kept at bay.

How Does Colon Hydrotherapy Work?
Colon hydrotherapy is a medical procedure to irrigate and revitalize your colon. It is usually performed by a certified practitioner who has undergone special training for this procedure. He makes use of sterilized or disposable medical equipment to pass 5-10 gallons of purified warm water into the colon through the anus. All toxins, trapped gases and accumulated waste are removed from your colon through this process and thus you feel deeply relaxed and rejuvenated.

Is Colon Hydrotherapy Painful?
Many people feel worried before this therapy, since they believe it to be a painful process. However, there is nothing that causes pain. Plenty of water is passed into your colon through the anus and then passed out using massage and other stimulation techniques. So, there is no piercing or any kind of discomfort. In fact, at the end of the therapy, you feel more refreshed. In rare cases, people report of some pain, which is generally the result of hesitation and tension. A professional therapist will not only make the whole procedure a lot easier for you but can also make you comfortable with his pre-therapy counseling session.

Can Colon Hydrotherapy Result in Constipation or Diarrhea?
Sometimes people report of constipation or frequent bowel movements following colon hydrotherapy. These conditions are the result of poor colon health. A very weak colon is unable to make regular bowel movements even after a few sessions of this therapy. For this, the colon requires to be strengthened and healed properly. Very rarely, diarrhea is experienced after this therapy. This is because extra water is induced into the colon, which makes the stool softer than usual. However, this is not a serious situation and does not last more than 3-4 days following colonic treatment.
Colon health is a priority for detoxifying the body, encouraging weight loss and maintaining a healthy lifestyle.

What Causes Pain Between Shoulder Blades?

The shoulder blade, otherwise known as the scapula is the bone structure in the upper back part of the body connecting the arm to the thorax (chest wall). The shoulder blade also forms part of the socket, which connects the upper arm to the socket. It is surrounded by muscles and tissues which cushion the bone structure allowing the shoulders to move smoothly. Thus, the shoulder blade is largely involved in the different movements of the human arms. Like any other parts of the body however, the shoulder blade may suffer swelling and inflammation, which lead to what is commonly referred to as shoulder blade pain.

However, pain between shoulder blades may be caused by a number of factors. The pain may be sourced from inflammation of the tissues or tendons surrounding the scapula or the shoulder blade. Muscles surrounding the shoulder blade may have been torn or strained due to some strenuous activities. The same case may also apply as regards the tendons and ligaments in the scapula region. Joint dislocations may also lead to shoulder blade pain as a result of a strong trauma after an accident or during a play of a sport. Shoulder blade pain may also involve infection or bone tumor in the region of the scapula; but cases of this type are very infrequent.

Although pain between shoulder blades may signal that there is something wrong with the tissues, joints, ligaments or muscles around and within the shoulder region, it is not however always the case. Not all types of pain between shoulder blades are indicative of infection, inflammation, or problems within the scapula region. Pain between the shoulder blades may be an indicator of a disease other than that which is directly related to infection in the scapula; such pain may be a signal warning from one of the organs of the body. This type of pain is considered as “referred pain”.

Shoulder blade pain may signal any pain from another part of the body the severity of which may range from mild to severe. Thus, the pain may be a referred pain from the lower part of the neck, or from the lower part of the back. This may be caused by too much stress or too much time spent in front of the computer. This may also indicate a posture problem. If the person has a bad posture, the spine may be affected and therefore it refers the stress and pressure to the shoulder blade area.

On the other hand, pain between shoulder blades may indicate severe medical problems or conditions in the other organs of the body. It may mean an impending heart attack; it has been documented that prior to a heart attack, most are experiencing pain between their shoulder blades. Gallbladder disease may also manifest in the form of pain between shoulder blades. This may oftentimes be accompanied by vomiting. It may also be caused by liver cancer and esophageal cancer or cancer in the esophagus due to an abnormal growth of cells and tumors in a person’s esophagus.

Kidney Cancer Symptoms Can be Subtle

The human body goes about its work without calling a lot of attention to what it is doing. Every once in a while, it gives a sign that something isn’t working quite right. A person may suddenly get a fever or discover that there is blood in the urine. These are two common kidney cancer symptoms that can often be mistaken for other conditions.

When visiting a doctor because of suspicious symptoms, it is important for him to know if the patient is at risk of getting kidney cancer. Some common risk factors include having undergone long-term dialysis, a family history of kidney cancer, smoking or being exposed to second-hand smoke and occupational exposure to chemicals or hazardous waste.

Once the risks have been assessed, the patient often undergoes a physical exam in order to discover any other possible kidney cancer symptoms. It is important to inform the doctor of any excessive, unexplained weight loss, consistent pain in the side or lower back, the presence of lumps in the abdomen or a general sense of being unwell. Doctors often check for high blood pressure and swelling of the lower extremities.

When a doctor suspects that a patient may have kidney cancer, he can perform a number of procedures in order to get a diagnosis. Attack-Kidney-Cancer may have the answers. The most common first step in diagnosing any condition is to perform a physical exam. If a doctor discovers symptoms of kidney cancer during a physical exam such as a fever, high blood pressure or masses in the abdomen or on the side, he will most likely proceed with further testing.

If a patient history and physical exam provide enough cause for further tests, a doctor often recommends blood and urine tests. Kidney cancer symptoms found by these tests often include unexplained rises in the level of certain substances like creatinine, which is filtered by the kidneys. If something is preventing the kidneys from filtering properly, doctors will want to perform further testing.

Additional testing including ultrasounds, computed tomography (CT) scans or magnetic resonance imaging (MRI) scans may become necessary if the previous results indicate the possibility of kidney cancer. A biopsy is an examination of tissues or liquids from the living body to determine the existence or cause of a disease. This is often done by extracting cells using a long needle. Biopsies can tell if a mass is cancerous or benign.

If kidney cancer symptoms and subsequent testing determines that a patient does, in fact, have kidney cancer, the doctor will advise a treatment plan. Treatment for kidney cancer can range from radiation therapy and surgery to chemotherapy and immunological therapy or a combination of treatments.

Seeing the possible symptoms of kidney cancer can be a frightening experience. More information can be found at http://www.attack-kidney-cancer.com. It is important to remember that many of the symptoms that can indicate kidney cancer can also indicate something as simple as a cyst or an infection. Whatever the cause of any symptom, it is always best to see a doctor for an accurate diagnosis.

Effect of nicotine and camellia sinensis (green tea extract) on histomorphology of developing thigh bone of chick embryo

Material and Method
This study was carried out at the poultry research institute (PRI) Rawalpindi and at Anatomy department of Army Medical College Rawalpindi. All the procedures were approved by Ethical Review Committee of Army Medical College Rawalpindi.
3.1 Sample Collection
40 fertile eggs of Fyoumi species of chick , were selected at zero hour of incubation.
3.1.1 Species selection
Fyoumi species of chick were selected for obtaining the specimen.
The eggs were collected from Poultry Research institute Punjab, Rawalpindi.
3.1.2 Specimen Collection
Sampling technique was random , eggs of abnormal shape, colour, size, texture and refrigerated eggs were excluded from the study.
3.1.3 Incubation
Eggs were placed in hatchery after properly fumigating and clearing the hatchery. Temperature was maintained at 37.5 degree centigrade ,the relative humidity was kept between 75% and proper ventilation was maintained. Rotation of eggs were done 4 hourly . Placement of eggs in hatchery was taken as day zero.
3.1.4 Study Groups
This study design comprises of 4 groups each comprising of 20 eggs of fouymi species.
Control group 1:(G1) Injected 0.1m of Normal saline.
Experimental group2:(G2)Injected 0.1m of Camellia sinensis (green tea extract).
Experimental group 3:(G3)Injected 0.1m of Nicotine solution.
Experimental group 4:(G4)Injected 0.1m of Nicotine solution and 0.1ml of Camellia sinensis.
Each group were injected with 0.1ml concentrations of respective solution.
3.2. Administeration of Different Working Solution
3.2.1 Control Group 1
Eggs were injected with insulin gauge needle, 0.1ml normal saline under laminar flow. First holes were made at the blunt end of eggs with the help of egg driller and then the 0.1ml quantity of solution were given to the eggs at 48 hr of incubation. Holes were sealed with paraffin wax after the injection.
3.2.2 Experimental Group 2
For this group 8g of dried leaves of Camellia sinensis in 100ml of hot distilled water for 15 minutes then filtering the solution. This solution of 0.1ml in quantity was administered to the experimental group 2 at 48 hr of incubation. Holes were sealed with paraffin wax after the injection.
3.2.3 Experimental Group 3
For this group 0.1ml of nicotine solution of 0.0001% concentration after preparing Nicotine stock solution from 1mg/ml,Nicotine Vial solution (purchased from Sigma Aldrich) were injected to group 3 at 48 hour of incubation . Holes were sealed with paraffin wax after the injection.
3.2.4 Experimental Group 4
In this group 0.1ml of Nicotine solution injected through the hole made at the blunt end of the eggs after the hole got sealed with paraffin wax, second hole made for the injection of 0.1% of camellia sinensis extract to the eggs at 48 hr of incubation. Holes were sealed with paraffin wax after the injection.
3.3 Collection of Specimen at 17 Days of Incubations
After incubating the eggs for 17 days, 10 eggs from each group were sacrificed and specimens were collected. Samples were collected by breaking the blunt end of eggs with the help of forceps. Separating the embryo from the yolk sac placing them in the formalin filled jars for 48 hour.
Results And Observation:
Aim of this study was to evaluate the effect of nicotine on the histomorphology of developing thigh bone of chick and role of camellia sinensis (green tea extract ).
SURVIVAL OF EMBRYO
The survival of control group (G1 )and experimental group (G2) at 17th day of incubation was significantly higher than the experimental group(G3) and (G4).Whereas in comparison of (G3) and (G4) the survival rate of G4 is significantly higher than that of (G3).
GROSS EXAMINATION
For 17th day old embryo the crown rump length was taken from vertex that is highest point between the eyeballs and tip of coccyx .A thread was taken whose one end was placed on the vertex and other end followed the curve of the back of embryo to the tip of coccyx . the distance covered by the thread was measured .Mean length of embryo in control group and experimental group(G2) was significantly more than that of(G3)and(G4).
Length of femur at 17th day of incubation was measured from the greater trochanter to the lateral condyle ( K.A. Alfonso-Torres etal., 2009).length of femur at 17th day of incubation were done it was significantly more in control group (G1 )and experimental group (G2) than the experimental group(G3) and (G4).
Histological Observation
By observing the height of proliferating zone and the hypertrophy zone by doing micrometery it was found that it was more in the experimental group (G3)and(G4) than control group (G1)and(G2) .
DISCUSSION
Nicotine is responsible of sever oxidative stress and camellia sinensis decrease it as the green tea resembles with control group but when it is administered along with nicotine it tries to overcome the oxidative stress of nicotine.Nicotine decrease the bone matrix formation by looking at the histomorphological changes.In a recent study of the eating habits of 2,018 women, consumption of mushrooms and green tea was linked to a 90% lower occurrence of breast cancer ( Zhang, M 2009).It has been suggested that antioxidant can modify some of histological changes produced by exposure to smoke (Klesges LM etal., 1998).Antioxidant provides protection against ischemia it can be useful in treating clinical states involving excess free radical production, such as fetal growth restriction and fetal hypoxia( OkataniYetal.,2001) Nicotine have a direct effect on bone metabolism by influencing the bone remodelling process. Nicotine suppressed cellular proliferation in rat osteosarcoma cells (Fang etal.,1991) and suppressed osteogenesis through a decrease in alkaline phosphatase (ALPase) and type1 collagen production by osteoblast(Tanka etal.,2005).In contrast, nicotine appears to stimulate osteoclast resorption by inducing bone resorbing cytokines, interleukin-1 (Norazlina etal.,2004).From different studies it has been suggested that nicotine was not only a direct inhibitor of osteoblast differentiation but also a regulator of osteoclast activity.

3.13 Photography
For photomicrography Olympus digitial camera (10mega pixel ) Stylus 1010 was used through the ocular of the Olympus CX21FSI having light microscope with the tube length of 160mm.The images were corrected and adjusted with respect to contrast, brightness, sharpness and color balance. The labelling of the pictures was done using computer softwares. The magnification was calculated according to the following formula (Anonymous,N.D): Power of eyepiece x Power of objective x Camera zoom.
Reference
* Niaz U,Hassan S,Ali S.Stress in women physician in Pakistan .Pak J Med Sci 2003;19(2):89-94
* Thun MJ,Henley SJ,Calle EE.Tobacco use and cancer:an epidemiologic perspective for geneticists.Oncogene 2002oct 21:21(48);7307-25.
* Environmental tobacco smoke . Microsoft Encarta Encyclopedia .Microsoft Corporation .993 -2004:14.0.0.0603
* Fang MA, Frost PJ,Iida-KleinA,HahnTJ(1991).Effect of nicotine on cellular function in UMR106-01 osteoblast-likecells Bone 12;283-286.
* Benowitz,N.l.In nicotine safety and toxicity.(Benowitz,N.l.,ed.) Oxford university press ,New York,1998,pp.3-28.
* Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892,Communicated by Melvin M. Grumbach, University of California, San Francisco, CA (received for review January 2, 2001 ); Effects of estrogen on growth plate senescence and epiphyseal fusion

* Hull MG, North k, Taylor H,Farrow A, Ford WC.Delayed conception and active and passive smoking .The avon longitudinal study of pregnancy and childhood study team. Fertile steril 2000 oct 21;21(48);7307-25.
* Goel P, Radotra A, Fadin A. Prematurity and low birth weight:effects of active and passive smoking during pregnancy .Can J public health .2001Jul-Aug:92(4):272-5
* Carmines EL, Gaworski CL, FaqiAS, Rajendran N. In utero exposure to 1R4Freference cigarette smoke :Evaluation of developmental toxicity.Toxicol Sci 2003;75:134-47.
* Galvin Rj, Ramp Wk, Lenz Lg. Smokeless tobacco contains a non-nicotine inhibitor of bone metabolism. Toxicol Appl Pharmacol 1988;95:292-300.
* Ramp WK, Lenz LG, Galvin RJS. Nicotine inhibits collagen synthesis and alkaline phosphatase activity, but stimulates DNA synthesis in osteoblast-like cells. Soc Exp Biol Med 1991;197:36-43.
* Bruder SP, Caplan AI Cellular and molecular events during embryonic bone development.
* MacDermott,A.b.,Role, L.wand Siegelbaum,S.A.Presynaptic ionotropic receptors and the control of transmitter release.Annu.Rev.Neuroscience., 1999, 22;443-485.

Increasing Awareness To Prevent The Major Causes Of Cancer

The best thing about cancer is that it can be averted. Changes in diet, lifestyle, and pretty much everything surrounding cholesterol, nicotine, and alcohol is the key to be cancer-free. But, it would be impossible for you not to have tasted food without cholesterol and have not drunk a glass of beer. So, to avert cancer, you can always try these lifestyle changes.

Filter the water you are currently drinking. Research have shown that the water we drink right off the sink can cause cancer. Several carcinogens are present in the drinking water that you deem to be safe.

If you plan on having a Sunday barbecue, make sure that you have marinated your barbecue for at least an hour before you grill them. We all know that grilling is a risky way of cooking meat as it can induce cancer but marinating your barbecue can cut the risk in half with the help of herbs that have antioxidants.

Coffee has been known to prevent brain cancer from developing to at least 40 percent. So, down 4-5 mugs of coffee or any type of coffee a day to help prevent tumors from growing on your brain. Coffee and caffeine is also known to prevent throat and mouth cancers.

Water down your risk for cancer by drinking 8 glasses of water a day. Water dilutes the chemicals that causes bladder cancer. It also flushes toxins out of the system.

Green vegetables help lower your chances of getting colon cancer. Not only does it provide you with enough natural fiber, but it is also a good source of magnesium that is important for proper cell division and replication.

While heading outdoors, choose the right colors to wear. Blue and red have better protection against UV rays than white and yellow so prefer to wear them. Prepare large hats and sunglasses to protect your body from the heat of the sun that can cause melanoma.

Take calcium supplements to help prevent colon cancer. This can also greatly help in preventing bone cancer as well. Calcium helps strengthen your bones as well as your immune system.

Small Cell Lung Cancer (SCLC) Treatment Market, 2016-2026 by Segmentation: Based on Product, Application and Region

According to the World Health Organization (WHO), 8.2 million people died from cancer around the world in 2012, and cancer is now one of the leading causes of death. Lung cancer is the leading cancer type and caused 1.59 million deaths in 2012.
Small cell lung cancer is two types –
* Oat cancer
* Combiner small cell cancer
The major risk factors for small cell lung cancer are tobacco, alcohol, unhealthy food and physical inactivity. Some chronic infections also causes cancer. Having family history of lung cancer and being effected with the HIV also risk factors for small cell lung cancer
Symptoms of small cell lung cancer include coughing, blood in sputum, wheezing, chest pain, and shortness of breath. Current treatments are not cure the cancer in some patients with small cell lung cancer.
To treat small cell lung cancer following treatments are available:
* Surgery
* Radiation therapy
* Chemotherapy
Doctors performed surgery to remove malignant tumor and lymph node.
Chemotherapy and radiation therapy given to the patient at a time to treat early stage of small cell lung cancer. Giving to treatments at a time to the patient is called concurrent chemo radiation.
Radiation therapy is given to the patient to shrink tumor cells as well as to relieve symptoms such as bleeding, cough, trouble swallowing and shortness of breath. Three-dimensional conformal radiation therapy (3D-CRT) and Intensity modulated radiation therapy (IMRT) are the two types of radiation methods used in the treatment.

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Small Cell Lung Cancer (SCLC) Treatment Market: Drivers and Restraints
According to World Health Organization, cancer is the leading cause of death and it accounts 8.2 million deaths in 2012. Lung cancer is the leading cancer among the other cancers. For instance, 1.59 million people died with lung cancer around the world. Changing life style, smoking, increased alcohol consumption, unhealthy food, air pollution and no physical activity are indirectly driving the market. International healthcare organizations such as World Health Organization (WHO), National Cancer Institute, American Cancer Society also providing guidelines for cancer patients. Governments in the emerging economies are providing awareness among the people about the cancer. The above are driving factors for small cell lung cancer market.
Cost of the treatment and lack of awareness among the people for early detection of cancer are restrains for small cell lung cancer market
Small Cell Lung Cancer (SCLC) TreatmentMarket: Segmentation
Small Cell Lung Cancer (SCLC) Treatment market is segmented into following types
Based on Treatment
* Radiation Therapy
* Three-dimensional conformal radiation therapy (3D-CRT)
* Intensity modulated radiation therapy (IMRT)
* Chemotherapy
* Platinum derivatives
* Topoisomerase Inhibitor
* Surgeries
Based on End User
* Hospital
* Hospital Pharmacies
* Drug store
* Ambulatory Surgical Center

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Small Cell Lung Cancer (SCLC) Treatment Market: Overview
Increasing awareness about cancer among common people and guidance from international organizations about the small cell lung cancer (SCLC) Treatment, the market is expected to have a healthy growth in the forecast period (2016-2026)
Small Cell Lung Cancer (SCLC) Treatment Market: Region- wise Outlook
Depending on geographic regions, the global Small Cell Lung Cancer (SCLC) Treatment market is segmented into seven key regions: North America, South America, Eastern Europe, Western Europe, Asia Pacific excluding Japan, Japan andMiddle East & Africa.
Small Cell Lung Cancer (SCLC) Treatment is high in North America because it is highly developed region, having good healthcare setup and people are having good awareness about health care. Asia Pacific is expected to grow at a remarkable CAGR. Europe also having good growth in this market.

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Small Cell Lung Cancer (SCLC) Treatment Market: Key Players
Some of the key players in this market are Teva parenteral medicines inc., Bristol myers co, Novartis AG, Elekta AB, Siemens Healthcare GmbH, Bedford laboratories and App pharmaceuticals llc

A Guide To Balding For Ladies

If you are a woman suffering from hair thinning, then you know all too well the emotions of insecurity, melancholy and nervousness that may come along with it. You’ve got no doubt thought of your choices rigorously, and found that there are an overwhelming variety of products in the marketplace, all making claims that theirs is the best. You’ve got additionally realized by now that most of the products on the market are geared particularly for men.

But women and men are very totally different physiologically, and a hair loss therapy that’s proper for men may not be the best option for women. In fact, simply getting sufficient information on what’s inflicting this drawback usually proves to be probably the most challenging a part of the entire ordeal.

For one factor, the principle reason for balding in males has been identified. It is DHT, the metabolite the holds the follicle together and makes it shrink until it dies. DHT is shaped when the enzyme 5-alpha reductase turns testosterone into DHT, which then interacts with the follicle and causes the loss of hair. Practically all treatments for males goal DHT.

Whereas it’s true that balding in women might be brought on by DHT, there are many different potential reasons as well that should be examined.

Thyroid Issues One widespread explanation for thinning hair in women, apart from DHT ranges, is an under active or overactive thyroid. As your body devotes increasingly more assets to dealing with the imbalance brought on by your thyroid, hair cells can shut all the way down to redirect their energy elsewhere.

Medicines There are quite a lot of medicine that can induce baldness or hair thinning. If you are taking new medicines and you observed that you are shedding more hair than normal, it’s strongly advised that you just go to your doctor and ask him more concerning the condition. You may either request for a new set of medicines that will not trigger the same uncomfortable side effects on you. Ignoring the situation may trigger irreversible baldness.

Examples of frequent medicines that may cause hair fall would be fenofibrate, naproxen, and pregabalin. These medication are associated indirectly with excessive cholesterol, arthritis, and pain. Should you take any one in all them, be very cautious concerning the number of strands that you may be dropping everyday. Anything more than regular is a legitimate cause for alarm.

There are numerous different medication that may cause the same effect, like medication for pimples, epilepsy, Parkinson’s disease, breast cancer, and thyroid problems. If you’re taking antibiotics or antifungal drugs orally, additionally, you will be susceptible to hair loss problems. Even some birth control tablets are recognized to trigger the identical concerns.

As well as, a number of medication commonly prescribed for hair thinning can actually cause you to lose more hair as a side effect.

Vitamin Deficiencies Vitamin deficiencies can usually cause you to lose your hair. The good news about these deficiencies is that once you begin getting the nutrient you might be deficient in, hair development can reoccur. Major loss of hair in women has been shown to be caused by deficiencies in Biotin, Vitamin D, Iron amongst different things.

Mechanical Damage Physical stress to the hair may cause hair loss in women as well. This could range from pulling it to hard, to itching and rubbing too excessively. A proper shampoo is an effective approach to shield the hair, scalp and follicle against mechanical damage.

Diet Most importantly, and one thing that you do not hear about often, is the fact that your eating regimen performs a huge role in hair problems. For proper development, a women’s hair truly requires very particular foods to be eaten, and very specific meals to be avoided. Any effective remedy should address your diet to be efficient for women.

Shampoo Your shampoo also can play a role in your hair loss. Many dangerous chemical substances, including sulfates and parabens, are widespread in most shampoos. Women affected by hair loss should immediately switch to a shampoo that is sulfate and paraben free, and preferably one with a base made from aloe and coconut oil to protect the hair shaft from mechanical damage and enhance the quantity of nutrients absorbed by the hair.

How Do Anti Sperm Antibodies Affect Vasectomy Reversal?

Several factors affect the infertility condition of a man. Certain drugs that you may be taking to treat a chronic ailment may contribute to your infertility condition. However, the most common and most difficult to treat is the development and production of anti sperm antibodies.

How do you explain anti sperm antibodies?

The anti sperm antibodies is a developed autoimmune system that triggers an allergic reaction to sperm. This means that the body perceives and treats the sperm as a threat. The immune system will then react by mobilizing the antibodies to search and destroy any sperm presence. If you have this condition, it would be difficult for you to impregnate a woman naturally.

The testicles protect the sperm from potential damage the auto immune system may cause. People who developed anti sperm antibody are capable of destroying their own sperm even if the testicles are already protecting them. The auto immune system goes right through the barrier and destroys the sperm. The antigens that attach themselves to the surface of the sperm make the whole search and destroy thing easier because they can easily track them.

The autoimmune system automatically detects the presence of the sperm and initiates a response. Unfortunately, the response triggered by the antigens is search and destroy. The antibodies would then stick to the surfaces of the sperms and tries to destroy their quality. This automatically destroys the function of the sperm. The extent of the damage depends on the sperm location and the volume of antibodies surrounding or attaching to them.

Potential effects of antibodies on the sperm

If the anti sperm antibodies attach themselves to the tail of the sperm, they lump together and make the sperm unmoving or immobile.

If the anti sperm antibodies attach themselves to the head of the sperm, they start to penetrate the sperm and prevents it from fertilizing the eggs. Anti sperm antibodies penetrating the sperm would make them unable to bind with the egg for fertilization.

Anti sperm antibodies

About 10% of men consulting about infertility have this common problem of anti sperm antibodies immune system. However, some women also developed anti sperm antibodies commonly called as sensitivity to sperm presence. Technically, sensitivity to sperm presence means that the cervical mucus of the woman is sensitive to any sperm presence, which initiates a response from the male’s body leading to the development of an anti sperm antibody. About 40% of married couples dealing with infertility problems are found to possess the anti sperm antibody autoimmune system.
Other factors that trigger anti sperm antibodies development

Several factors may trigger the development of the anti sperm antibodies. One of the most common factors is the injury on the testicles. The other factor could be a twisted testicular sack, which would result to the development of anti sperm antibodies. Sometimes, infection may mess up the immune system and produce such condition.

Vasectomy reversal and anti sperm antibodies
Studies show that the vasectomy reversal procedure has the capability to trigger the formation or development of the anti sperm antibodies. The procedure could also potentially develop other risks such as varicocele, testicular biopsy, and cancer. The procedure could also develop undescended testicles and congenital absence of the male’s vas deferens. About 70% of men who had undergone the procedure developed the anti sperm antibodies. A semen analysis would help the doctor diagnose the health of your sperm and if there is any presence of anti sperm antibodies. The doctor may also request a cervical test in case your semen sample show any sign of anti sperm antibodies to know the real cause of this condition.

What You Need To Know About Prostate Cancer

As its name, prostate cancer is a cancerous disease that develops in your prostate gland. The cancer cells can spread from the prostate to other parts of your body, such as your bones and lymph. Nowadays, prostate cancer is one of the most common types of cancer. Therefore, if you are a man, it is very important for you to have regular checkup to keep a close eye to your prostate condition. In this case, if you are indeed suffering from prostate cancer, it can be noticed early and treated properly before it develops into a more dangerous condition.

Prostate cancer symptoms

There are many symptoms that can occur when you are suffering from prostate cancer. They can be extremely varied in term of its severity depending on your particular case and condition. Learning about prostate cancer symptoms is a wise move because if you can recognize them early, then you can immediately visit a doctor to get proper checkup and diagnosis before it grows into something serious.

Many experts consider prostate cancer as a silent killer because early symptoms of prostate cancer do not surface until it has spread. In the early stage, most prostate cancer is a slow-growing tumor and thus some people do not experience any symptom. Due to this nature, it is important to have a regular checkup to really make sure that the cancerous condition does not exist or it can be detected as early as possible.

Some aggressive tumors do give symptoms of prostate cancer like backaches and pelvis or hip pains, which normally are caused by cancer cells that have spread to the bones. When the prostate cancer grows further, it enlarges and affects other organs. During this stage, different symptoms of prostate cancer start showing themselves, which normally are related with urination problems. Several common symptoms of prostate cancer are pain during ejaculation, difficulty to urinate, experience dribbling after urination, blood in urine, weight loss, frequent urination while sleeping, and a weak flow of urine.

Prostate tests

If you feel that you are at risk of prostate cancer, then it is essential for you to get prostate tests to determine whether it really exists or not. There are two types of test, the first is to determine whether a prostate cancer is present or not and the second is to find out the stage of the prostate tumor. Prostate specific antigen (PSA) test and digital rectal exam (DRE) are two tests to diagnose the presence of prostate cancer. On the other hand, transrectal ultrasound and prostate biopsy are used to determine the stage of the prostate cancer.

A PSA test is performed by analyzing the blood sample to find out the level of prostate specific antigen, a substance produced by the prostate gland. If you have high level of PSA, it may indicate some kind of prostate diseases, such as enlarged prostate, infection, or cancer. A DRE is used to determine whether a tumor exists in your prostate or not. The prostate gland is located in front of the rectum and in order to check for abnormalities in the prostate, the doctor will insert a gloved, lubricated finger into your rectum. It is unwise to wait for symptoms of prostate cancer to appear. Therefore, it is essential to take a PSA or DRE test once a year to make sure that the prostate stays healthy.

Treatments and preventive measures are available

Another thing that needs to be considered carefully is that even if you are diagnosed with prostate cancer, there are many available treatments out there. You should not feel overwhelmed and feel that there is nothing you can do to survive this condition. As long as you have a qualified and experienced doctor with the support from friends and other family members, you have a good chance to get rid of this prostate cancer. Prostate cancer is definitely a grim condition, but you should keep positive attitude in order to combat the disease.

In addition, you should maintain a healthy life style, which includes a healthy diet and sufficient exercise or physical activities. With better overall health, you will help your body to fight against sicknesses and diseases that can attack your body. There is no surefire way to prevent prostate cancer from happening, but you can fight with every possible way that you can think of. Understanding prostate cancer symptoms, regular checkup, and lead a healthy lifestyle are the things that you should put on the top of your list.